Celiac plexus block in a patient with upper abdominal pain caused by diabetic gastroparesis

provided the original work is properly cited. CC Diabetic gastroparesis is characterized by delayed gastric emptying, which stems from long-standing diabetic neuromyopathy. The symptoms of gastroparesis include early satiety, nausea, vomiting, postprandial fullness and upper abdominal pain [1]. Here, we present the case of a patient with a 20-year history of diabetes mellitus and a 2-year history of gastroparesis. The patient was suffering from frequent nausea, vomiting and upper abdominal pain, which remained unresponsive to medical treatments. A 40-year-old woman was referred to our pain clinic by the department of nephrology with a chief complaint of intractable upper abdominal pain. She had been given a score of 9–10 on the visual analogue scale (VAS). The pain was described to be cramping and bitter as the patient remained in a knee-chest crouched position. She presented a known case of juvenile diabetes which had first been diagnosed at the age of 13. As the age of 38, she had diagnosed with diabetic gastroparesis. She had been admitted for 3–4 days each month for upper abdominal pain management. At the time of the referral, her blood pressure was 120/80 mmHg and her pulse rate was 100 /min. Her height and body weight were 151 cm and 38.4 kg, respectively. The laboratory examinations revealed the following, HbA1c, glucose, BUN/creatinine and albumin levels; 7.1%, 131 mg/dl, 50/2.3 mg/dl and 4.8 g/dl, respectively. At the time of her final admission, the intractable pain overshadowed nausea and vomiting. As the pain characteristics showed a visceral origin, we decided to perform a thoracic epidural block in an attempt to block the sympathetic nerve in the upper abdominal area. The thoracic epidural block was performed using a paramedian approach at the T7-T8 level with 10 ml of 1% mepivacaine. The patient fell asleep 5 minutes after the end of the nerve block procedure. After a 2-hour sleep, she was returned to the ward with no pain complaint. She was discharged pain-free the next day but returned to the hospital for recurrent abdominal pain 2 weeks later. On this admission, her VAS score was 6–7. She was referred to our department for a more sustainable form of pain control. This time, we decided to perform celiac plexus block with alcohol. A left celiac plexus block was performed with 10 ml absolute alcohol first. The right-side celiac plexus nerve was suspended for the significant pain reduction. She was discharged from the hospital with no complications after 2 days. She experienced significantly reduced pain thereafter and was only been admitted to the hospital twice for recurrent nausea and vomiting over the 6-month follow-up period. Gastroparesis is a functional disorder presenting delayed emptying of the gastric contents which is more prevalent in women. GI symptoms are present in 76% of diabetic patients, and 34% of patient reports abdominal pain [2]. The origin of this abdominal pain is a source of debate, but it is suggested that the symptoms are related to a neurogenic disturbance at the enteric nervous system level or the spinal/brain level [3]. Our patient had been suffering from nausea, vomiting and upper abdominal pain for 2 years. She had received strong pain medications including intravenous tramadol and meperidine on her admissions. To control the abdominal pain, opioids, tricyclic antidepressants, gabapentin and pregabalin had been suggested. Our patient was already suffering from chronic gastroparesis symptoms and was referred to our pain clinic for her intractable